Minocycline and Magnesium As Neuroprotective Agents for Ischemic Stroke: A Systematic Review
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چکیده
منابع مشابه
Neuroprotective agents in ischemic stroke: past failures and future opportunities
Tissue plasminogen activator is the only US FDA-approved therapy for acute ischemic stroke treatment. There is a need for other therapies such as neuroprotective agents that can be used in acute ischemic stroke patients. Many neuroprotective agents have been shown to be promising after testing in animal models of acute stroke, but when tested in patients, efficacy signals are not consistent or ...
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Anuradha Patel1* and Sergey V Pisklakov2* 1Associate Professor, Section Chief, Pediatric Anesthesia, Department of Anesthesiology and Perioperative Care New Jersey School of Medicine, Newark, New Jersey, USA 2Assistant Professor, Director of Neuroanesthesia Service, Chairman of Clinical Competence Committee, Department of Anesthesiology and Perioperative Care, New Jersey School of Medicine, New...
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BACKGROUND AND PURPOSE Several studies have suggested that exposure to "triggers," could precipitate the onset of ischemic stroke (IS). We performed a systematic review of the potential triggers of IS. METHODS Two independent reviewers identified studies published between January 1980 and June 2010 from MEDLINE and Embase. Where appropriate, odds ratios (ORs) were combined. RESULTS A total ...
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Background and purpose: This meta-analysis review aimed to investigate the effect of resistance training on functional performance and physiological factors in patients with ischemic stroke. Materials and methods: The search was conducted in PubMed, Web of Science, and Scopus using related keywords. All articles were reviewed, but 22 studies that met the inclusion criteria were included after ...
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Cerebral ischemia initiates a cascade of detrimental events including glutamate-associated excitotoxicity, intracellular calcium accumulation, formation of Reactive oxygen species (ROS), membrane lipid degradation, and DNA damage, which lead to the disruption of cellular homeostasis and structural damage of ischemic brain tissue. Cerebral ischemia also triggers acute inflammation, which exacerb...
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ژورنال
عنوان ژورنال: Cureus
سال: 2020
ISSN: 2168-8184
DOI: 10.7759/cureus.12339